
Thinning Hair
Understanding thinning hair
Thinning hair is most often caused by genetics and hormones, with stress, illness, iron or thyroid problems, childbirth and ageing also playing a part. For gradual thinning, Skin Anatomy in Southwell offers E50 hair exosome treatment, applied to the scalp after microneedling to support the follicle environment. Sudden or patchy hair loss should be checked by your GP first.
Everyone sheds hair every day as part of the normal growth cycle, but when follicles gradually shrink or spend less time in their growing phase, hair becomes finer and sparser. In men this often shows as a receding hairline or thinning crown; in women it is more commonly a widening parting or an overall loss of density. Hair can also shed heavily for a few months after a stressful event, illness, surgery or childbirth, a pattern that often recovers on its own.
Exosomes are tiny vesicles released by cells that carry proteins, lipids and nucleic acids between cells as part of their natural communication. E50 HAIR exosomes are made using the manufacturer's ENTR® technology: the exosomes are collected from salmon testes cells and cultivated in embryonic stem cell media. After microneedling creates fine channels in the scalp, the exosome solution is applied so it can reach the skin around the follicles, where it aims to calm inflammation and support a healthier environment for hair growth.
It is important to be clear about what this treatment is and is not. E50 is a cosmetic product rather than a licensed medicine, the research on exosomes for hair is still emerging, and results vary between people. It is not a treatment for medical hair-loss conditions such as alopecia areata or scarring alopecia. We have seen encouraging changes in some clients, and at your free consultation we will talk honestly about whether it is likely to help you. Treatment is for adults aged 18 and over.

What causes thinning hair?
- Genetic pattern hair loss in men and women
- Hormonal changes, including menopause and after childbirth
- Stress, illness, surgery or rapid weight loss
- Low iron, low vitamin D or thyroid problems
- Tight hairstyles and heat or chemical damage
- Some medicines, and natural ageing
Everyone’s skin is different. At your free consultation we look at the likely causes of your concern, and your medical history, before recommending anything.
Treatments for thinning hair
Many clients get the best results from a combination of treatments. We recommend a plan only after a free, no-obligation consultation — and we will tell you honestly what improvement is realistic.
E50 HAIR exosome treatment combines scalp microneedling with a salmon-derived exosome solution made using ENTR® technology. The aim is to calm inflammation and support the environment around the follicles, helping hair look thicker and healthier. A course of several sessions is usually recommended, and changes are gradual, so we review progress with photographs over a few months. Results vary, it suits gradual thinning rather than bald areas, and it is not suitable if you have a fish allergy.
Before & After
Unretouched before and after photos of treatment at Skin Anatomy. Drag the handle to compare — individual results vary.


Self-care tips
Simple habits that support your skin alongside — or before — any treatment for thinning hair.
- Eat a balanced diet with enough protein, iron and vitamin D
- Be gentle with wet hair and limit heat styling and bleaching
- Avoid tight ponytails, braids and extensions that pull on the roots
- Manage stress where you can, as it can trigger extra shedding
- Protect your scalp from the sun, especially where hair is thinner
- Take progress photos in the same light to track changes over time
Thinning Hair: your questions answered
Do exosomes really work for thinning hair?
How many exosome sessions will I need for thinning hair?
When will I see results from hair exosome treatment?
Is E50 hair treatment suitable for women?
Does scalp microneedling hurt?
Who should not have exosome treatment for hair?
Where can I get hair loss treatment near Nottingham?
Related skin concerns
- Acne ScarsRolling, boxcar and ice-pick scars softened by resurfacing and collagen-building treatments.
- Pigmentation & Sun DamageSun spots, age spots and uneven tone evened out with laser resurfacing and skin regeneration.
- Enlarged Pores & TextureRefine visible pores and rough, uneven texture for smoother, clearer-looking skin.
- Dull, Dehydrated SkinRestore hydration, bounce and glow to tired, lacklustre skin.
Easy to reach from across Nottinghamshire
Skin Anatomy is at 17 Queen Street, Southwell, Nottinghamshire NG25 0AA, around 30 minutes from Nottingham, 15 minutes from Newark-on-Trent and 25 minutes from Mansfield by car (approximate). Clients visit us for treatment for thinning hair from Southwell and the surrounding villages, as well as Nottingham, Newark-on-Trent, Mansfield, Bingham and Ollerton. Find travel and parking tips for your town:
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